abstract：BACKGROUND:Pulmonary vein isolation by cryoballoon ablation is an accepted method of treating atrial fibrillation. Little data exist regarding factors affecting late electrical reconnection of pulmonary veins following cryoballoon ablation. OBJECTIVE:To investigate factors determining pulmonary vein reconnection in pa...

journal_title：Heart rhythm

authors： Ghosh J,Martin A,Keech AC,Chan KH,Gomes S,Singarayar S,McGuire MA

更新日期：2013-09-01 00:00:00

abstract：BACKGROUND:For late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) assessment of atrial scar to guide management and targeting of ablation in atrial fibrillation (AF), an objective, reproducible method of identifying atrial scar is required. OBJECTIVE:To describe an automated method for operator-...

journal_title：Heart rhythm

authors： Malcolme-Lawes LC,Juli C,Karim R,Bai W,Quest R,Lim PB,Jamil-Copley S,Kojodjojo P,Ariff B,Davies DW,Rueckert D,Francis DP,Hunter R,Jones D,Boubertakh R,Petersen SE,Schilling R,Kanagaratnam P,Peters NS

更新日期：2013-08-01 00:00:00

abstract：BACKGROUND:Both schizophrenia and epilepsy have been linked to increased risk of sudden cardiac death (SCD). We hypothesized that DNA variants within genes previously associated with schizophrenia and epilepsy may contribute to an increased risk of SCD. OBJECTIVE:To investigate the contribution to SCD susceptibility o...

journal_title：Heart rhythm

authors： Huertas-Vazquez A,Teodorescu C,Reinier K,Uy-Evanado A,Chugh H,Jerger K,Ayala J,Gunson K,Jui J,Newton-Cheh C,Albert CM,Chugh SS

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Despite isolated reports of Brugada syndrome (BrS) in the inferior or lateral leads, the prevalence and prognostic value of ST elevation in the peripheral electrocardiographic (ECG) leads in patients with BrS remain poorly known. OBJECTIVE:To study the prevalence, characteristics, and prognostic value of ty...

journal_title：Heart rhythm

authors： Rollin A,Sacher F,Gourraud JB,Pasquié JL,Raczka F,Duparc A,Mondoly P,Cardin C,Delay M,Chatel S,Derval N,Denis A,Sadron M,Davy JM,Hocini M,Jaïs P,Jesel L,Haïssaguerre M,Probst V,Maury P

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Asymptomatic cerebral embolus (ACE) detected by diffusion-weighted magnetic resonance imaging (DW-MRI) following atrial fibrillation (AF) ablation has been reported at varying rates with different ablation techniques. OBJECTIVE:To evaluate the incidence of ACE after phased radiofrequency ablation for AF wit...

journal_title：Heart rhythm

authors： Wieczorek M,Hoeltgen R,Brueck M

更新日期：2013-07-01 00:00:00

abstract：BACKGROUND:Reciprocal ST-segment depression simulating additional subendocardial ischemia is commonly observed in ST-segment elevation myocardial infarction. OBJECTIVE:To study the mechanism and characterization of the whole reciprocal electrocardiogram (ECG) patterns induced by acute coronary artery occlusion at diff...

journal_title：Heart rhythm

authors： Noriega FJ,Jorge E,Arzamendi D,Cinca J

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Cardiac resynchronization therapy (CRT) and atrial ablation procedures currently lack a noninvasive imaging modality for reliable treatment planning and monitoring. Electromechanical wave imaging (EWI) is an ultrasound-based method that has previously been shown to be capable of noninvasively and transmurall...

journal_title：Heart rhythm

authors： Provost J,Gambhir A,Vest J,Garan H,Konofagou EE

更新日期：2013-06-01 00:00:00

abstract：BACKGROUND:Catheter contact is important for radiofrequency (RF) ablation. Local electrical catheter-to-tissue coupling has been described as a tool to objectively measure contact. OBJECTIVE:We hypothesized that pulmonary vein isolation (PVI) ablation using electrical coupling information (ECI) would yield higher rate...

journal_title：Heart rhythm

authors： Gaspar T,Sih H,Hindricks G,Eitel C,Sommer P,Kircher S,Rolf S,Arya A,Teplitsky L,Piorkowski C

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Small-diameter implantable cardioverter-defibrillator (ICD) Sprint Fidelis and Riata leads have been recalled owing to an increased risk of lead failure, thus arousing the suspicion that lead size might be a critical issue. OBJECTIVE:To compare the incidence of failure of small-diameter (≤8 F) and standard-...

journal_title：Heart rhythm

authors： Rordorf R,Poggio L,Savastano S,Vicentini A,Petracci B,Chieffo E,Klersy C,Landolina M

更新日期：2013-02-01 00:00:00

abstract：BACKGROUND:Patients with chronic right ventricular pacing (RVP) upgraded to cardiac resynchronization therapy (CRT) have been excluded from the majority of clinical trials of CRT. Little is known about the predictors of response in this population. We hypothesized that reversal of RVP-induced electrical dyssynchrony (i...

journal_title：Heart rhythm

authors： Rickard J,Cheng A,Spragg D,Cantillon D,Chung MK,Tang WH,Wilkoff BL,Varma N

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Carvedilol and its analogues suppress delayed afterdepolarizations (DADs) and catecholaminergic polymorphic ventricular tachycardias by direct action on the cardiac ryanodine receptor type 2 (RyR2). OBJECTIVE:To test a hypothesis that carvedilol analogue may also prevent triggered activities (TAs) through t...

journal_title：Heart rhythm

authors： Maruyama M,Xiao J,Zhou Q,Vembaiyan K,Chua SK,Rubart-von der Lohe M,Lin SF,Back TG,Chen SR,Chen PS

更新日期：2013-01-01 00:00:00

abstract：BACKGROUND:Ranolazine exhibits a synergistic effect in combination with class III drugs to suppress atrial fibrillation. OBJECTIVE:To investigate whether a combination therapy affects repolarization and provokes ventricular tachyarrhythmias (VT) in a sensitive model of proarrhythmia. METHODS:Thirty-seven rabbits were...

journal_title：Heart rhythm

authors： Frommeyer G,Kaiser D,Uphaus T,Kaese S,Osada N,Rajamani S,Belardinelli L,Breithardt G,Eckardt L,Milberg P

更新日期：2012-12-01 00:00:00

abstract：BACKGROUND:Antitachycardia pacing (ATP) can reduce implantable cardioverter-defibrillator shocks, but its use in children and patients with congenital heart disease (CHD) is not well described. OBJECTIVE:To review the efficacy of ATP in children and patients with CHD. METHODS:We reviewed implantable cardioverter-defi...

journal_title：Heart rhythm

authors： Kalra Y,Radbill AE,Johns JA,Fish FA,Kannankeril PJ

更新日期：2012-11-01 00:00:00

abstract：BACKGROUND:The early repolarization pattern (ERP) is common and associated with risk of sudden cardiac death. ERP is heritable, and mutations have been described in syndromatic cases. OBJECTIVE:To conduct a meta-analysis of genome-wide association studies to identify common genetic variants influencing ERP. METHODS:W...

journal_title：Heart rhythm

authors： Sinner MF,Porthan K,Noseworthy PA,Havulinna AS,Tikkanen JT,Müller-Nurasyid M,Peloso G,Ulivi S,Beckmann BM,Brockhaus AC,Cooper RR,Gasparini P,Hengstenberg C,Hwang SJ,Iorio A,Junttila MJ,Klopp N,Kähönen M,Laaksonen MA,

更新日期：2012-10-01 00:00:00

abstract：BACKGROUND:Atrial premature contractions (APCs) are well described to precede the initiation of paroxysmal atrial fibrillation (pAF). However, whether APC characteristics alter with progression of the arrhythmia is unknown. OBJECTIVE:To determine the APC characteristics in terms of burden and relative coupling interva...

journal_title：Heart rhythm

authors： Brooks AG,Rangnekar G,Ganesan AN,Salna I,Middeldorp ME,Kuklik P,Baumert M,Roberts-Thomson KC,Sanders P

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Mildly symptomatic heart failure (HF) patients were shown to derive substantial clinical benefit from cardiac resynchronization therapy with defibrillator (CRT-D) in Multicenter Automatic Defibrillator Implantation Trial in Cardiac Resynchronization Therapy. However, the relationship between functional capac...

journal_title：Heart rhythm

authors： Brenyo A,Goldenberg I,Moss AJ,Rao M,McNitt S,Huang DT,Zareba W,Barsheshet A

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:Recurrences are common within the first months following atrial fibrillation (AF) ablation. However, prior studies using only intermittent ECG recording have not shown a powerful correlation with ultimate response. OBJECTIVE:The purpose of this study was to use continuous AF monitoring with an implanted mon...

journal_title：Heart rhythm

authors： Pokushalov E,Romanov A,Corbucci G,Bairamova S,Losik D,Turov A,Shirokova N,Karaskov A,Mittal S,Steinberg JS

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:The optimal energy setting for endoscopic pulmonary vein (PV) isolation (PVI) has not yet been determined. OBJECTIVE:To assess the influence of varying energy settings on the efficacy and safety of endoscopic PVI. METHODS:In the current prospective study, 30 patients with paroxysmal atrial fibrillation wer...

journal_title：Heart rhythm

authors： Metzner A,Wissner E,Schoonderwoerd B,Burchard A,Tilz R,Fürnkranz A,Rillig A,Mathew S,Ouyang F,Kuck KH

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:T-peak to T-end (TPE) interval on the electrocardiogram is a measure of myocardial dispersion of repolarization and is associated with an increased risk of ventricular arrhythmias. The genetic factors affecting the TPE interval are largely unknown. OBJECTIVE:To identify common genetic variants that affect t...

journal_title：Heart rhythm

authors： Marjamaa A,Oikarinen L,Porthan K,Ripatti S,Peloso G,Noseworthy PA,Viitasalo M,Nieminen MS,Toivonen L,Kontula K,Peltonen L,Havulinna AS,Jula A,O'Donnell CJ,Newton-Cheh C,Perola M,Salomaa V

更新日期：2012-07-01 00:00:00

abstract：BACKGROUND:Ventricular tachyarrhythmias are an important cause of morbidity and mortality in cardiac sarcoidosis. To date, the prevalence and incidence of ventricular tachycardia/ventricular fibrillation (VT/VF) in this population remain unknown. OBJECTIVES:To determine the prevalence and incidence of ventricular tach...

journal_title：Heart rhythm

authors： Betensky BP,Tschabrunn CM,Zado ES,Goldberg LR,Marchlinski FE,Garcia FC,Cooper JM

更新日期：2012-06-01 00:00:00

abstract：BACKGROUND:The origin of outflow tract ventricular tachycardia (OTVT) can be predicted from a surface electrocardiogram: indexes of R-wave amplitudes in leads V(1) and V(2) are used to differentiate a right origin from a left origin, while the axis of lead I differentiates an anterior origin from a posterior origin. In...

journal_title：Heart rhythm

authors： Anter E,Frankel DS,Marchlinski FE,Dixit S

更新日期：2012-05-01 00:00:00

abstract：:Since the discovery of atrial natriuretic peptide (ANP) in 1981, significant progress has been made in understanding the mechanism of its release and its role in salt and water balance in the body. It has also become clear that ANP plays a key role in cardiac electrophysiology, modulating the autonomic nervous system ...

journal_title：Heart rhythm

authors： Perrin MJ,Gollob MH

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND:Persistent atrial fibrillation (AF) is associated with a high risk of recurrence after electrical cardioversion. OBJECTIVE:We examined if long-term supplementation with omega-3 polyunsaturated fatty acids in fish oils commenced >1 month prior to electrical cardioversion and continued thereafter reduces recu...

journal_title：Heart rhythm

authors： Kumar S,Sutherland F,Morton JB,Lee G,Morgan J,Wong J,Eccleston DE,Voukelatos J,Garg ML,Sparks PB

更新日期：2012-04-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:High-intensity frequency ultrasound (HIFU) can achieve pulmonary vein isolation (PVI), but severe complications have happened. An esophageal temperature (ET)-guided safety algorithm was implemented. We investigated medium-term outcome. METHODS:After left atrial access, HIFU was applied until c...

journal_title：Heart rhythm

authors： Neven K,Metzner A,Schmidt B,Ouyang F,Kuck KH

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:There is controversy whether proceduralist-directed, nurse-administered propofol sedation (PDNAPS) is safe. OBJECTIVE:To assess the frequency of adverse events when PDNAPS is used for implantable cardioverter-defibrillator (ICD)-related procedures and to determine the patient and procedural characteristics ...

journal_title：Heart rhythm

authors： Sayfo S,Vakil KP,Alqaqa'a A,Flippin H,Bhakta D,Yadav AV,Miller JM,Groh WJ

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:KCNQ1 (Kv7.1), together with its KCNE β subunits, plays a pivotal role both in the repolarization of cardiac tissue and in water and salt transport across epithelial membranes. Nedd4/Nedd4-like (neuronal precursor cell-expressed developmentally downregulated 4) ubiquitin-protein ligases interact with the KCN...

journal_title：Heart rhythm

authors： Krzystanek K,Rasmussen HB,Grunnet M,Staub O,Olesen SP,Abriel H,Jespersen T

更新日期：2012-03-01 00:00:00

abstract：BACKGROUND:The pulmonary veins (PVs) and the PV-LA (left atrium) junction are established sources of triggers initiating atrial fibrillation. In addition, they have been implicated in the maintenance of arrhythmia. OBJECTIVE:To undertake high-density electrophysiological characterization of the right superior PV-LA ju...

journal_title：Heart rhythm

authors： Lee G,Spence S,Teh A,Goldblatt J,Larobina M,Atkinson V,Brown R,Morton JB,Sanders P,Kistler PM,Kalman JM

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:Although J-wave elevation in the inferolateral leads could be related to idiopathic ventricular fibrillation (IVF), little is known about the pathophysiologic characteristics of J-wave elevation in patients with IVF. OBJECTIVE:This study aimed to determine the relationship between augmentation of J-wave ele...

journal_title：Heart rhythm

authors： Mizumaki K,Nishida K,Iwamoto J,Nakatani Y,Yamaguchi Y,Sakamoto T,Tsuneda T,Kataoka N,Inoue H

更新日期：2012-02-01 00:00:00

abstract：BACKGROUND:The relationship between shocks, device programming, and atrial fibrillation (AF) with a rapid ventricular rate (AF + RVR) using continuous daily monitoring has not been studied in large number of patients with implantable cardioverter-defibrillators (ICDs). OBJECTIVE:The aim of this analysis was to determi...

journal_title：Heart rhythm

authors： Fischer A,Ousdigian KT,Johnson JW,Gillberg JM,Wilkoff BL

更新日期：2012-01-01 00:00:00

abstract：OBJECTIVES:The aim of this multicenter study was to evaluate the device- and procedure-related safety of a novel force-sensing radiofrequency (RF) ablation catheter capable of measuring the real-time contact force (CF) and to present CF data and its possible implications on patient safety. BACKGROUND:The clinical outc...

journal_title：Heart rhythm

authors： Kuck KH,Reddy VY,Schmidt B,Natale A,Neuzil P,Saoudi N,Kautzner J,Herrera C,Hindricks G,Jaïs P,Nakagawa H,Lambert H,Shah DC

更新日期：2012-01-01 00:00:00

abstract：BACKGROUND:In normal atrial and ventricular tissue, the electrical wavefronts are mediated by the fast sodium current (I(Na)), whereas in sinoatrial and atrioventricular nodal tissue, conduction is mediated by the slow L-type calcium current (I(Ca,L)). However, it has not been shown whether the same tissue can exhibit ...

journal_title：Heart rhythm

authors： Chang MG,Sato D,de Lange E,Lee JH,Karagueuzian HS,Garfinkel A,Weiss JN,Qu Z

更新日期：2012-01-01 00:00:00

abstract：:In the United States, sudden cardiac death accounts for an estimated 300,000 to 350,000 cases each year, with 80,000 presenting as the first manifestation of a preexisting, sometimes unrecognized, coronary artery disease. Acute myocardial infarction (AMI)-induced ventricular fibrillation frequently occurs without warn...

journal_title：Heart rhythm

authors： Di Diego JM,Antzelevitch C

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:The reported complication rate of catheter ablation of atrial fibrillation (AF) varies. OBJECTIVE:Our goal was to assess temporal trends and the effect of both institutional and individual operators' experience on the incidence of complications. METHODS:All patients undergoing AF ablation at Johns Hopkins ...

journal_title：Heart rhythm

authors： Hoyt H,Bhonsale A,Chilukuri K,Alhumaid F,Needleman M,Edwards D,Govil A,Nazarian S,Cheng A,Henrikson CA,Sinha S,Marine JE,Berger R,Calkins H,Spragg DD

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Prediction of sustained ventricular tachycardia (VT)/ventricular fibrillation (VF) could help to guide preventive interventions in at-risk patients. The QRST integral (∫QT) reflects intrinsic repolarization properties. OBJECTIVE:The objective of this study was to determine whether intracardiac ∫QT predicts ...

journal_title：Heart rhythm

authors： Tereshchenko LG,Ghanem RN,Abeyratne A,Swerdlow CD

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Negative tracheal pressure (NTP) during tracheal obstruction in obstructive apnea increases vagal tone and causes pronounced shortening of the atrial effective refractory period (AERP), thereby perpetuating atrial fibrillation (AF). The role of different atrial potassium channels under those conditions has n...

journal_title：Heart rhythm

authors： Linz D,Schotten U,Neuberger HR,Böhm M,Wirth K

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Pharmacologic and ablative therapies for atrial fibrillation (AF) have suboptimal efficacy. Newer gene-based approaches that target specific mechanisms underlying AF are likely to be more efficacious in treating AF. Parasympathetic signaling appears to be an important contributor to AF substrate. OBJECTIVE:...

journal_title：Heart rhythm

authors： Aistrup GL,Cokic I,Ng J,Gordon D,Koduri H,Browne S,Arapi D,Segon Y,Goldstein J,Angulo A,Wasserstrom JA,Goldberger JJ,Kadish AH,Arora R

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Complex fractionated atrial electrograms (CFAEs) and regions of high dominant frequency (DF) both may identify sites critical to the maintenance of atrial fibrillation (AF). CFAEs may be defined by either (1) complex multicomponent electrograms (EGMs) and/or continuous electrical activity (multicomponent/con...

journal_title：Heart rhythm

authors： Lee G,Roberts-Thomson K,Madry A,Spence S,Teh A,Heck PM,Kumar S,Kistler PM,Morton JB,Sanders P,Kalman JM

更新日期：2011-11-01 00:00:00

abstract：:Among the most serious problems associated with heart failure is the increased likelihood of life-threatening arrhythmias. Both triggered and reentrant arrhythmias in heart failure may arise as a result of aberrant intracellular Ca cycling. This article presents some new ideas, based on recent studies, about how alter...

journal_title：Heart rhythm

authors： Aistrup GL,Balke CW,Wasserstrom JA

更新日期：2011-11-01 00:00:00

abstract：BACKGROUND:Ventricular late potentials (VLPs) have been known to be a predictor of lethal ventricular arrhythmias (L-VAs); however, detection of other arrhythmogenic signals within the QRS complex remains obscure. OBJECTIVE:The aim of this study was to evaluate whether abnormal intra-QRS high-frequency powers (IQHFP) ...

journal_title：Heart rhythm

authors： Tsutsumi T,Takano N,Matsuyama N,Higashi Y,Iwasawa K,Nakajima T

更新日期：2011-10-01 00:00:00

abstract：BACKGROUND:Little is known about the tachyarrhythmias relating to respiration. Case reports presented patients with respiratory cycle-dependent atrial tachycardias (RCATs), which cyclically emerge after starting inspiration and cease during expiration. OBJECTIVE:The aim of the present study was to elucidate the preval...

journal_title：Heart rhythm

authors： Yamamoto T,Hayashi M,Miyauchi Y,Murata H,Horie T,Igawa O,Kato T,Mizuno K

更新日期：2011-10-01 00:00:00